"In humans, exercise improves what scientists call "executive function," the set of abilities that allows you to select behavior that's appropriate to the situation, inhibit inappropriate behavior and focus on the job at hand in spite of distractions. Executive function includes basic functions like processing speed, response speed, and working memory, the type used to remember a house number while walking from the car to a party."
Exercise on the Brain [NYT]
Nootrópicos (smartdrugs, drogas inteligentes, potenciadores cognitivos) son sustancias artificiales (medicamentos como piracetam, hydergina, citicolina, fosfatidilserina, vinpocetina, etc.) o naturales (suplementos nutricionales, vitaminas, aminoácidos, hormonas, hierbas, etc. como vitaminas B, piroglutamato, Gingko Biloba, fenilalanina, DHEA, pregnenolona, etc.) que se utilizan para mejorar la capacidad cognitiva (memoria, atención, etc.) en personas con trastornos o normales.
sábado, noviembre 10, 2007
lunes, octubre 08, 2007
Los consejos de Hyla Cass para mejorar la capacidad mental
Top Tips for Natural Mind Enhancement
If your razor-sharp intellect is blunted and your memory is failing you, here's what to do for that extra mental edge:
Take a B complex supplement that provides 50 mg each of vitamins B3, B5, B6, 50 mcg of B12 and 400 mg of folic acid (in addition to what's in your multivitamin); also take 1,000 mg of DHA/EPA or eat fish three times a week.
Your mind-boosting formula can contain any or all of the following. Experiment with the individual products to get your own special mix.
Start with 60 mg of ginkgo
add in 200 mg of phosphatidyl choline
200 mg of DMAE
10 mg of vinpocetine
and 50 mg of phosphatidyl serine. These doses are acceptable in a combined formula, but again, use your own response as the measure.
Other Tips:
Do some aerobic exercise to oxygenate your brain, raise endorphins, and as an added bonus, burn some fat.
Take a bath with essential oils of lemon, eucalyptus, cinnamon or peppermint dispersed in the water, or scent your room with them.
Listen to stimulating music.
Maximize the light in your room with natural daylight or full-spectrum lighting.
Por Hyla Cass, que no sé cuanta credibilidad tiene pero no parece mal orientado. Hay otros consejos (stress, energía, ánimo) en la nota Top tips for natural highs.
En realidad que las vitaminas B sean todas en 50 mg es algo infundado y más bien porque es así como se venden.
If your razor-sharp intellect is blunted and your memory is failing you, here's what to do for that extra mental edge:
Take a B complex supplement that provides 50 mg each of vitamins B3, B5, B6, 50 mcg of B12 and 400 mg of folic acid (in addition to what's in your multivitamin); also take 1,000 mg of DHA/EPA or eat fish three times a week.
Your mind-boosting formula can contain any or all of the following. Experiment with the individual products to get your own special mix.
Start with 60 mg of ginkgo
add in 200 mg of phosphatidyl choline
200 mg of DMAE
10 mg of vinpocetine
and 50 mg of phosphatidyl serine. These doses are acceptable in a combined formula, but again, use your own response as the measure.
Other Tips:
Do some aerobic exercise to oxygenate your brain, raise endorphins, and as an added bonus, burn some fat.
Take a bath with essential oils of lemon, eucalyptus, cinnamon or peppermint dispersed in the water, or scent your room with them.
Listen to stimulating music.
Maximize the light in your room with natural daylight or full-spectrum lighting.
Por Hyla Cass, que no sé cuanta credibilidad tiene pero no parece mal orientado. Hay otros consejos (stress, energía, ánimo) en la nota Top tips for natural highs.
En realidad que las vitaminas B sean todas en 50 mg es algo infundado y más bien porque es así como se venden.
sábado, octubre 06, 2007
Hoy estaba acelerado y era por la hydergina
Hoy a la mañana estaba bastante acelarado y quería hacer cosas y rápido
pero tenía un poco de ansiedad.
pero tenía un poco de ansiedad.
No entendía bien qué pasaba, hasta que me acordé de que había tomado 2,25
mg de hydergina que hacía mucho que no tomaba. Casi seguro que esa fue la
causa.
Por lo tanto voy a tomar la mitad de la dosis la próxima vez.
domingo, septiembre 23, 2007
Rhodiola ayuda en la depresion y a estudiantes
Parece que sigue el interés en la hierba Rhodiola como adaptógeno, mejorador del ánimo y de la agilidad mental.
Yo la he probado pero no de una marca reconocida. No noté un claro efecto. Recomiendo, si pueden, comprar la del Swedish Herbal Institut o alguna que tenga respaldo.
La buena noticia es que según el artículo en Canadá se está cultivando en la provincia de Alberta. Puede ser que tengamos un producto accesible y de buena calidad.
Meanwhile, Wikman and the Swedish Herbal Institute, which makes a rhodiola
extract called SHR-5, have continued laboratory and human tests. In 2000,
they reported that SHR-5 protects snail embryos from heat, copper, and
oxidative stress. When given the herb extract, fewer of the embryos died
after exposure to these stressors than did embryos not given the extract.
Also in 2000, Wikman and his colleagues in Russia published results from a
randomized, double-blind trial of university students who took SHR-5 at the
end of a semester. Students taking the herb for 20 days fared better on
measures of fatigue and mental performance than did students who took a
placebo. Another study published in 2000 found an antifatigue effect of the
herb among 56 physicians working night shifts.
sciencenews.org
Yo la he probado pero no de una marca reconocida. No noté un claro efecto. Recomiendo, si pueden, comprar la del Swedish Herbal Institut o alguna que tenga respaldo.
La buena noticia es que según el artículo en Canadá se está cultivando en la provincia de Alberta. Puede ser que tengamos un producto accesible y de buena calidad.
Meanwhile, Wikman and the Swedish Herbal Institute, which makes a rhodiola
extract called SHR-5, have continued laboratory and human tests. In 2000,
they reported that SHR-5 protects snail embryos from heat, copper, and
oxidative stress. When given the herb extract, fewer of the embryos died
after exposure to these stressors than did embryos not given the extract.
Also in 2000, Wikman and his colleagues in Russia published results from a
randomized, double-blind trial of university students who took SHR-5 at the
end of a semester. Students taking the herb for 20 days fared better on
measures of fatigue and mental performance than did students who took a
placebo. Another study published in 2000 found an antifatigue effect of the
herb among 56 physicians working night shifts.
sciencenews.org
domingo, septiembre 09, 2007
Conviene distribuir el estudio en el tiempo
Estudiar en grandes bloques no ayuda al aprendizaje a largo plazo. Conviene hacerlo por partes y repasar, es decir distribuir el estudio en el tiempo.
In other words, as reported in the August issue of Current Directions in Psychological Science, �massing� all the study on a single topic into a single session reduces long-term retention. It�s better to leave it alone for a while and then return to it. Rohrer and Pashler also wanted to see if the duration of study breaks might make a difference in learning. It did. When two study sessions were separated by breaks ranging from five minutes to six months, with a final test given six months later, students did much better if their break lasted at least a month. So, rather than distribute their study of some material across just a few days, as millions of school children do when given a different list of vocabulary or spelling words each week, students would be better off seeing the same words throughout the school year.
futurepundit.com
In other words, as reported in the August issue of Current Directions in Psychological Science, �massing� all the study on a single topic into a single session reduces long-term retention. It�s better to leave it alone for a while and then return to it. Rohrer and Pashler also wanted to see if the duration of study breaks might make a difference in learning. It did. When two study sessions were separated by breaks ranging from five minutes to six months, with a final test given six months later, students did much better if their break lasted at least a month. So, rather than distribute their study of some material across just a few days, as millions of school children do when given a different list of vocabulary or spelling words each week, students would be better off seeing the same words throughout the school year.
futurepundit.com
sábado, julio 21, 2007
Vuelve el uso de LSD en psicoterapias
The Royal Society of Chemistry reports that a research project investigating the potential benefits of LSD assisted psychotherapy for people with terminal illnesses has been given the go-ahead by the Swiss authorities.
mindhacks.com
mindhacks.com
jueves, julio 19, 2007
Anoche tome hydergina, hoy mi combo y voy mejor
Ayer tenía que escribir un trabajo pero no podía, la magnitud de la tarea
me tenía mal (sumado a preocupaciones personales de otro tipo).
me tenía mal (sumado a preocupaciones personales de otro tipo).
Tomé en forma sublingual una última dosis de hydergina de 1.5 mg que tenía.
Sentí algún pequeño efecto. Igual no pude trabajar.
Al irme a dormir me sentía todavía alerta. Tomé una pequeña dosis de
ansiolítico (benzodiacepina), ojo esto no es para jugar, pero lo comento
porque puede tener que ver con el efecto final. Dormí bastante bien, me
pregunto qué habrá tenido que ver en esto la hydergina.
Al despertarme hoy bastante temprano (hay buen sol y eso ayuda a despertar
y al ánimo) y antes de desayunar tomé en ayunas dosis normales de DMAE (lo
vengo tomando hace unos días a este controvertido suplemento), TMG,
piracetam, un poco de cinc y tomé mate cocido con una pizca de ginseng rojo
y jengibre. Después un vaso de leche, no tenía mucha hambre pero hay que
aportar algo de proteínas.
Como resultado me siento mejor (a pesar de que tengo los mismos problemas)
y ahora estoy escribiendo com mayor facilidad. Incluso tipeo mejor. No
quiero agrandar la cosa ni promover el uso de nada, solamente reportar para
mi propio control y que ustedes comenten.
Lo único diferente que agregué a mi dieta ayer fueron semillas de lino
molidas para agregar omega 3 (que se sabe son buenos para el cerebro pero
esto es una dosis baja) y otros nutrientes.
Si tienen éxito con algún suplemento que los ayude sobre todo en tareas de
estudio y escritura me interesa.
Un producto del que quisiera tener más conocimiento por experiencias es la
hupericina (huperzia, Huperzine A).
miércoles, julio 18, 2007
Alguien experimento con hupericina?
No encuentro muchos reportes sobre el uso de hupericina (huperzia serrata, hupericine).
Además de inhibir la degradación de la acetilcolina tiene otras propiedades, pero no sé si en una persona que no tenga graves problemas funciona bien. He visto algunos estudios en jóvenes estudiantes que parecen indicar efectividad o reportes de mayor concentración, pero no muchos coemntarios en foros.
Si alguien quiere comentar sería interesante.
Además de inhibir la degradación de la acetilcolina tiene otras propiedades, pero no sé si en una persona que no tenga graves problemas funciona bien. He visto algunos estudios en jóvenes estudiantes que parecen indicar efectividad o reportes de mayor concentración, pero no muchos coemntarios en foros.
Si alguien quiere comentar sería interesante.
lunes, julio 09, 2007
Recordatorio sobre nuestra lista de discusion
Si existe alguien que lea esto y además se interesa en el tema, lo animo a que deje comentarios si los tiene (puede hacerlo en forma anónima) y que se una a nuestra lista de discusión en Yahoo! Grupos.
Las discusiones se pueden seguir por email o mediante la página web.
Allí podemos tratar temas en forma más privada y responder preguntas prácticas. Ya somos unos cuantos.
Las discusiones se pueden seguir por email o mediante la página web.
Allí podemos tratar temas en forma más privada y responder preguntas prácticas. Ya somos unos cuantos.
domingo, julio 01, 2007
La importancia de las proteinas en el desayuno
En un estudio se vió que el hábito de algunos estudiantes de incluir jamón y queso en el desayuno los ayudaba en el rendimiento escolar.
El buen efecto se atribuye a que un desayuno rico en proteínas produce una liberación más lenta de glucosa.
Report: Ideal breakfast has ham, cheese
LONDON, June 24 (UPI) -- A scientific study of British students' eating habits has found eating ham and cheese for breakfast can significantly improve cognitive functioning.
...
"It is all down to the glucose release of the breakfast into the bloodstream. The slower the release, the better the pupils performed," Benton said of his study's findings.
...
"The high protein in the breakfast will release into the system slowly, and therefore it will suppress the appetite for longer, and prevent children from snacking," he told the newspaper.
sciencedaily.com
El buen efecto se atribuye a que un desayuno rico en proteínas produce una liberación más lenta de glucosa.
Report: Ideal breakfast has ham, cheese
LONDON, June 24 (UPI) -- A scientific study of British students' eating habits has found eating ham and cheese for breakfast can significantly improve cognitive functioning.
...
"It is all down to the glucose release of the breakfast into the bloodstream. The slower the release, the better the pupils performed," Benton said of his study's findings.
...
"The high protein in the breakfast will release into the system slowly, and therefore it will suppress the appetite for longer, and prevent children from snacking," he told the newspaper.
sciencedaily.com
miércoles, junio 27, 2007
Merk nutrition y Office of Dietary Supplements NIH
Buenos sitios de referencia en nutrición y suplementos dietarios:
Merk Nutrition: General Considerations
Office of Dietary Supplements • NIH Clinical Center • National Institutes of Health
Merk Nutrition: General Considerations
Office of Dietary Supplements • NIH Clinical Center • National Institutes of Health
miércoles, junio 20, 2007
Rehabilitacion Biomecanica Avanzada del trauma cerebral
Leyendo el diario me enteré de esta técnica que no conocía.
"Advanced Biomechanical Rehabilitation" cuya
traducción al castellano es: Rehabilitación Biomecánica Avanzada.
• ABR es el único método de rehabilitación basado en la biomecánica
que proporciona una recuperación de la estructura músculo-esquelética
y funciones motoras a niños y jóvenes adultos con daño cerebral.
http://www.abrtherapy.com.ar
"Advanced Biomechanical Rehabilitation" cuya
traducción al castellano es: Rehabilitación Biomecánica Avanzada.
• ABR es el único método de rehabilitación basado en la biomecánica
que proporciona una recuperación de la estructura músculo-esquelética
y funciones motoras a niños y jóvenes adultos con daño cerebral.
http://www.abrtherapy.com.ar
martes, junio 12, 2007
La Isradipina de uso en hipertension frenaria el parkinson
La Isradipina, una droga conocida y de uso en Argentina (DYNACIRC SRO NOVARTIS
Calcioantagonista Antihipertensivo ) frena el parkinson en un modelo de la enfermedad en ratones.
Explicado sencillamente y sin mayores exactitudes el mecanismo protector consiste en que la isradipina bloquea los canales de calcio y así hace que la neurona deteriorada que produce dopamina (son limitadas y tienden a morir especialmente en el parkinson) deje de usar calcio para activar su funcionamiento y vuelva a usar sodio como una neurona sana y joven.
La droga podría también beneficiar al hacer necesario menor dosis de medicaciones como la L-DOPA y mantenerla eficaz y no tener que usar cada vez dosis mayores como les pasa a los pacientes de parkinson.
Se habla también del posible uso preventivo y terapéutico en parkinson.
Drug slows and may halt Parkinson's disease
CHICAGO -- Northwestern University researchers have discovered a drug that slows – and may even halt – the progression of Parkinson's disease. The drug rejuvenates aging dopamine cells, whose death in the brain causes the symptoms of this devastating and widespread disease.
...
Dopamine is a critical chemical messenger in the brain that affects a person's ability to direct his movements. In Parkinson's disease, the neurons that release dopamine die, causing movement to become more and more difficult.
...
"Our hope is that this drug will protect dopamine neurons, so that if you began taking it early enough, you won't get Parkinson's disease, even if you were at risk. " said Surmeier, who heads the Morris K. Udall Center of Excellence for Parkinson's Disease Research at Northwestern. "It would be like taking a baby aspirin everyday to protect your heart."
Isradipine may also significantly benefit people who already have Parkinson's disease. In animal models of the disease, Surmeier's team found the drug protected dopamine neurons from toxins that would normally kill them by restoring the neurons to a younger state in which they are less vulnerable.
The principal therapy for Parkinson's disease patients currently is L-DOPA, which is converted in the brain to dopamine. Although L-DOPA relieves many symptoms of the disease in its early stages, the drug becomes less effective over time. As the disease progresses, higher doses of L-DOPA are required to help patients, leading to unwanted side-effects that include involuntary movements. The hope is that by slowing the death of dopamine neurons, isradipine could significantly extend the time in which L-DOPA works effectively.
"If we could double or triple the therapeutic window for L-DOPA, it would be a huge advance," Surmeier said.
...
Because he's a physiologist, Surmeier decided to investigate whether the electrical activity of dopamine neurons might provide a clue to their vulnerability. All neurons in the brain use electrical signals to do their job, much like digital computers.
First, Surmeier observed that dopamine neurons are non-stop workers called pacemakers. They generate regular electrical signals seven days a week, 24 hours a day, just like pacemaker cells in the heart. This was already known. But then he probed more deeply and discovered something very strange about these dopamine neurons.
Most pacemaking neurons use sodium ions (like those found in table salt) to produce electrical signals. But Surmeier found that adult dopamine neurons use calcium instead.
Sodium is a mild mannered ion that does its job without causing a whit of trouble to the cell. Calcium ions, however, are wild and rambunctious.
...
"The reliance upon calcium was a red flag to us," Surmeier said. Calcium ions need to be chaperoned by the cell almost as soon as they enter to keep them from causing trouble, he noted. The cell has to sequester them or keep pumping them out. This takes a lot of energy.
...
Surmeier theorized that the non-stop stress on the dopamine neurons explains why they are more vulnerable to toxins and die at a more rapid rate as we age.
...
When the neurons are young, Surmeier found they actually use sodium ions to do their work. But as the neurons age, they become more and more dependent on the troublesome calcium and stop using sodium. This calcium dependence – and the stress it causes the neurons --is what makes them more vulnerable to death.
What would happen, Surmeier wondered, if he simply blocked the calcium's route into the adult neuron cells" Would the neurons revert to their youthful behavior and start using sodium again"
"The cells had put away their old childhood tools in the closet. The question was if we stopped them from behaving like adults would they go into the closet and get them out again"" Surmeier asked. "Sure enough, they did."
When he gave the mice isradipine, it blocked the calcium from entering the dopamine neuron. At first, the dopamine neurons became silent. But within a few hours, they had reverted to their childhood ways, once again using sodium to get their work done.
"This lowers the cells' stress level and makes them much more resistant to any other insult that's going to come along down the road. They start acting like they're youngsters again," Surmeier said.
The next step will be launching a clinical study.
"This animal study suggests that calcium channel blockers, drugs currently used to reduce blood pressure, might someday be used to slow the steady progression of Parkinson's disease," said Walter J. Koroshetz, M.D., deputy director of the NINDS.
Calcioantagonista Antihipertensivo ) frena el parkinson en un modelo de la enfermedad en ratones.
Explicado sencillamente y sin mayores exactitudes el mecanismo protector consiste en que la isradipina bloquea los canales de calcio y así hace que la neurona deteriorada que produce dopamina (son limitadas y tienden a morir especialmente en el parkinson) deje de usar calcio para activar su funcionamiento y vuelva a usar sodio como una neurona sana y joven.
La droga podría también beneficiar al hacer necesario menor dosis de medicaciones como la L-DOPA y mantenerla eficaz y no tener que usar cada vez dosis mayores como les pasa a los pacientes de parkinson.
Se habla también del posible uso preventivo y terapéutico en parkinson.
Drug slows and may halt Parkinson's disease
CHICAGO -- Northwestern University researchers have discovered a drug that slows – and may even halt – the progression of Parkinson's disease. The drug rejuvenates aging dopamine cells, whose death in the brain causes the symptoms of this devastating and widespread disease.
...
Dopamine is a critical chemical messenger in the brain that affects a person's ability to direct his movements. In Parkinson's disease, the neurons that release dopamine die, causing movement to become more and more difficult.
...
"Our hope is that this drug will protect dopamine neurons, so that if you began taking it early enough, you won't get Parkinson's disease, even if you were at risk. " said Surmeier, who heads the Morris K. Udall Center of Excellence for Parkinson's Disease Research at Northwestern. "It would be like taking a baby aspirin everyday to protect your heart."
Isradipine may also significantly benefit people who already have Parkinson's disease. In animal models of the disease, Surmeier's team found the drug protected dopamine neurons from toxins that would normally kill them by restoring the neurons to a younger state in which they are less vulnerable.
The principal therapy for Parkinson's disease patients currently is L-DOPA, which is converted in the brain to dopamine. Although L-DOPA relieves many symptoms of the disease in its early stages, the drug becomes less effective over time. As the disease progresses, higher doses of L-DOPA are required to help patients, leading to unwanted side-effects that include involuntary movements. The hope is that by slowing the death of dopamine neurons, isradipine could significantly extend the time in which L-DOPA works effectively.
"If we could double or triple the therapeutic window for L-DOPA, it would be a huge advance," Surmeier said.
...
Because he's a physiologist, Surmeier decided to investigate whether the electrical activity of dopamine neurons might provide a clue to their vulnerability. All neurons in the brain use electrical signals to do their job, much like digital computers.
First, Surmeier observed that dopamine neurons are non-stop workers called pacemakers. They generate regular electrical signals seven days a week, 24 hours a day, just like pacemaker cells in the heart. This was already known. But then he probed more deeply and discovered something very strange about these dopamine neurons.
Most pacemaking neurons use sodium ions (like those found in table salt) to produce electrical signals. But Surmeier found that adult dopamine neurons use calcium instead.
Sodium is a mild mannered ion that does its job without causing a whit of trouble to the cell. Calcium ions, however, are wild and rambunctious.
...
"The reliance upon calcium was a red flag to us," Surmeier said. Calcium ions need to be chaperoned by the cell almost as soon as they enter to keep them from causing trouble, he noted. The cell has to sequester them or keep pumping them out. This takes a lot of energy.
...
Surmeier theorized that the non-stop stress on the dopamine neurons explains why they are more vulnerable to toxins and die at a more rapid rate as we age.
...
When the neurons are young, Surmeier found they actually use sodium ions to do their work. But as the neurons age, they become more and more dependent on the troublesome calcium and stop using sodium. This calcium dependence – and the stress it causes the neurons --is what makes them more vulnerable to death.
What would happen, Surmeier wondered, if he simply blocked the calcium's route into the adult neuron cells" Would the neurons revert to their youthful behavior and start using sodium again"
"The cells had put away their old childhood tools in the closet. The question was if we stopped them from behaving like adults would they go into the closet and get them out again"" Surmeier asked. "Sure enough, they did."
When he gave the mice isradipine, it blocked the calcium from entering the dopamine neuron. At first, the dopamine neurons became silent. But within a few hours, they had reverted to their childhood ways, once again using sodium to get their work done.
"This lowers the cells' stress level and makes them much more resistant to any other insult that's going to come along down the road. They start acting like they're youngsters again," Surmeier said.
The next step will be launching a clinical study.
"This animal study suggests that calcium channel blockers, drugs currently used to reduce blood pressure, might someday be used to slow the steady progression of Parkinson's disease," said Walter J. Koroshetz, M.D., deputy director of the NINDS.
domingo, junio 10, 2007
Los 14 mejores alimentos para el cerebro
Pon buen alimento en tu cerebro cada día. Eres lo que comes. Cada célula en tu cuerpo se hace de nuevo cada 5 meses. Eres literalmente lo que comes.
En el libro Super Foods hay una lista de los 14 mejores alimentos, que son todos muy buenos para la función del cerebro. Intente incorporarlos en su dieta cada semana.
Aquí está la lista: arándanos (la mayoría de las bayas, pero especialmente arándanos), brócoli, habas (pinto, navy, lima, garbanzos, lentejas, sugar snap peas, guisantes), naranjas, avena, calabaza (puré, no pastel), salmón silvestre, espinaca, soja, té (especialmente verde), tomates, pavo (o pollo), nueces, y yogur.
Según el lugar a las "bayas" se las llama "frutos rojos" y a las "habas" chauchas, arvejas.
De:
Put good food into your brain each day. You are what you eat. Every cell in your body makes itself new every 5 months. You literally are what you eat. In the book Super Foods there is a list of the 14 best foods, which are all very good for brain function. Try to incorporate them into your diet every week. Here s the list: blueberries (most berries, but especially blueberries), broccoli, beans (pinto, navy, lima, chickpeas, lentils, sugar snap peas, peas), oranges, oats, pumpkin (squash not pie), wild salmon, spinach, soy, tea (especially green), tomatoes, turkey (or chicken), walnuts, and yogurt.
amenclinics.com
En el libro Super Foods hay una lista de los 14 mejores alimentos, que son todos muy buenos para la función del cerebro. Intente incorporarlos en su dieta cada semana.
Aquí está la lista: arándanos (la mayoría de las bayas, pero especialmente arándanos), brócoli, habas (pinto, navy, lima, garbanzos, lentejas, sugar snap peas, guisantes), naranjas, avena, calabaza (puré, no pastel), salmón silvestre, espinaca, soja, té (especialmente verde), tomates, pavo (o pollo), nueces, y yogur.
Según el lugar a las "bayas" se las llama "frutos rojos" y a las "habas" chauchas, arvejas.
De:
Put good food into your brain each day. You are what you eat. Every cell in your body makes itself new every 5 months. You literally are what you eat. In the book Super Foods there is a list of the 14 best foods, which are all very good for brain function. Try to incorporate them into your diet every week. Here s the list: blueberries (most berries, but especially blueberries), broccoli, beans (pinto, navy, lima, chickpeas, lentils, sugar snap peas, peas), oranges, oats, pumpkin (squash not pie), wild salmon, spinach, soy, tea (especially green), tomatoes, turkey (or chicken), walnuts, and yogurt.
amenclinics.com
martes, mayo 29, 2007
Citicolina mejora la memoria en ratas tratadas con bromazepam
Citicoline antagonizes bromazepam-induced amnesia in rats
X. Antón Alvarez 1 *, Begoña Vecino 1, Juan Enrique Perea 2, Danilo Daniele 2, Ramón Cacabelos 1
1EuroEspes Biomedical Research Center, A Coruña, Spain
2Laboratorios Baliarda, Buenos Aires, Argentina
email: X. Antón Alvarez ( euroespes@lcg.servicom.es )
*Correspondence to X. Antón Alvarez, Department of Neuropharmacology, EuroEspes Biomedical Research Center, Santa Marta de Babío, 15166-Bergondo, A Coruña, Spain. Tel and Fax: 34-81-78 05 05.
Funded by:
Laboratories Baliarda, Argentina
EuroEspes Foundation, Spain
Keywords
citicoline • bromazepam • acquisition • retention • memory • amnesia • motor co-ordination • exploratory activity
Abstract
Citicoline is an endogenous intermediate in the biosynthesis of brain phospholipids and acetylcholine used for the treatment of neurodegenerative processes associated with head trauma, stroke, brain aging, cerebrovascular pathology and Alzheimer's disease. In this study we have investigated the effects of citicoline on acquisition and retention in passive avoidance and spatial discriminative learning tasks in control rats and in bomazepam-treated animals. Interactions of citicoline with bromazepam on exploratory behaviour (anxiolytic/sedative activity) and motor co-ordination (myorelaxing activity) were also evaluated to test the specificity of the cognitive effects of citicoline. Our results indicate that citicoline reverses bromazepam-induced amnesia, improves retention in control rats, and has no significant effects on spontaneous activity and motor co-ordination when given alone or in combination with bromazepam. According to these results we conclude that citicoline acts as a promnesic and anti-amnesic drug with no sedative-myorelaxing activity in rats. Therefore, this compound might be of use for the specific treatment of cognitive impairments associated with the chronic use of benzodiazepines. © 1997 John Wiley & Sons, Ltd.
Digital Object Identifier (DOI)
10.1002/(SICI)1099-1077(199711/12)12:6<547::AID-HUP922>3.0.CO;2-T
wiley.com
X. Antón Alvarez 1 *, Begoña Vecino 1, Juan Enrique Perea 2, Danilo Daniele 2, Ramón Cacabelos 1
1EuroEspes Biomedical Research Center, A Coruña, Spain
2Laboratorios Baliarda, Buenos Aires, Argentina
email: X. Antón Alvarez ( euroespes@lcg.servicom.es )
*Correspondence to X. Antón Alvarez, Department of Neuropharmacology, EuroEspes Biomedical Research Center, Santa Marta de Babío, 15166-Bergondo, A Coruña, Spain. Tel and Fax: 34-81-78 05 05.
Funded by:
Laboratories Baliarda, Argentina
EuroEspes Foundation, Spain
Keywords
citicoline • bromazepam • acquisition • retention • memory • amnesia • motor co-ordination • exploratory activity
Abstract
Citicoline is an endogenous intermediate in the biosynthesis of brain phospholipids and acetylcholine used for the treatment of neurodegenerative processes associated with head trauma, stroke, brain aging, cerebrovascular pathology and Alzheimer's disease. In this study we have investigated the effects of citicoline on acquisition and retention in passive avoidance and spatial discriminative learning tasks in control rats and in bomazepam-treated animals. Interactions of citicoline with bromazepam on exploratory behaviour (anxiolytic/sedative activity) and motor co-ordination (myorelaxing activity) were also evaluated to test the specificity of the cognitive effects of citicoline. Our results indicate that citicoline reverses bromazepam-induced amnesia, improves retention in control rats, and has no significant effects on spontaneous activity and motor co-ordination when given alone or in combination with bromazepam. According to these results we conclude that citicoline acts as a promnesic and anti-amnesic drug with no sedative-myorelaxing activity in rats. Therefore, this compound might be of use for the specific treatment of cognitive impairments associated with the chronic use of benzodiazepines. © 1997 John Wiley & Sons, Ltd.
Digital Object Identifier (DOI)
10.1002/(SICI)1099-1077(199711/12)12:6<547::AID-HUP922>3.0.CO;2-T
wiley.com
domingo, mayo 13, 2007
Movimiento de ojos para mejorar la memoria
Según un estudio mover los ojos lateralmente por 30 segundos mejora la memoria al hacer que los hemisferios cerebrales interactúen más entre si.
Se le presentaron listas de palabras a los sujetos y algunos hicieron movimientos horizontales de ojos por 30 segundos, tras los cuales reconocieron más palabras.
Sugieren probar mover los ojos de esta manera cuando uno no puede recordar por ejemplo dónde dejó un objeto.
Moving Your Eyes Improves Memory, Study Suggests
If you're looking for a quick memory fix, move your eyes from side-to-side for 30 seconds, researchers say.
Horizontal eye movements are thought to cause the two hemispheres of the brain to interact more with one another, and communication between brain hemispheres is important for retrieving certain types of memories.
Se le presentaron listas de palabras a los sujetos y algunos hicieron movimientos horizontales de ojos por 30 segundos, tras los cuales reconocieron más palabras.
Sugieren probar mover los ojos de esta manera cuando uno no puede recordar por ejemplo dónde dejó un objeto.
Moving Your Eyes Improves Memory, Study Suggests
If you're looking for a quick memory fix, move your eyes from side-to-side for 30 seconds, researchers say.
Horizontal eye movements are thought to cause the two hemispheres of the brain to interact more with one another, and communication between brain hemispheres is important for retrieving certain types of memories.
lunes, abril 23, 2007
Nuevo blog de Juan Carlos
Como hacía tiempo que no sabía de las actividades de Juan Carlos me dí una vuelta por drogasinteligentes.com y veo que abrió un weblog:
blogs.periodistadigital.com/francotirador.php
Los temas prometen ser más variados que los nootrópicos y de mayor interés para los europeos. Espero que le vaya muy bien.
blogs.periodistadigital.com/francotirador.php
Los temas prometen ser más variados que los nootrópicos y de mayor interés para los europeos. Espero que le vaya muy bien.
viernes, abril 20, 2007
El propranolol disminuye la melatonina y podria usarse en depresiones estacionales
Siempre hay que tener en cuenta las interacciones de lo que uno toma y de las sustancias que las drogas tienden a disminuir. En este caso el efecto del propranolol de disminuir la melatonina es probado como tratamiento de la depresión estacional donde se altera la producción de melatonina por falta de luz.
Clinical Trial of Propranolol for Seasonal Affective Disorder
The purpose of this study is to determine what dose of a new timed-release tablet of the drug propranolol will reduce secretion of the hormone melatonin in healthy volunteers. This study will also determine whether suppressing melatonin will improve depressive symptoms in people with seasonal affective disorder (SAD).
SAD (sometimes referred to as winter depression) is a condition in which people experience depression as a result of seasonal variations in light. Human brains have a circadian pacemaker that regulates many body functions. As the seasons change and light duration varies, the circadian pacemaker regulates seasonal behavior by transmitting a signal of day length to the pineal gland, which secretes the hormone melatonin. Melatonin secretion increases in the winter as the duration of light decreases.
Otros artículos:
El propranolol se absorbe mejor de día.
Clinical Trial of Propranolol for Seasonal Affective Disorder
The purpose of this study is to determine what dose of a new timed-release tablet of the drug propranolol will reduce secretion of the hormone melatonin in healthy volunteers. This study will also determine whether suppressing melatonin will improve depressive symptoms in people with seasonal affective disorder (SAD).
SAD (sometimes referred to as winter depression) is a condition in which people experience depression as a result of seasonal variations in light. Human brains have a circadian pacemaker that regulates many body functions. As the seasons change and light duration varies, the circadian pacemaker regulates seasonal behavior by transmitting a signal of day length to the pineal gland, which secretes the hormone melatonin. Melatonin secretion increases in the winter as the duration of light decreases.
Otros artículos:
El propranolol se absorbe mejor de día.
martes, abril 17, 2007
Hallaron en la cola de quirquincho efectos positivos en la memoria
Sabía que la Huperzia Serrata es la fuente de la hupericina que se vende como suplemento para la memoria por su efcto inhibidor de la acetilcolintransferasa, la enzima que degrada el neurotransmisor acetilcolina. No sabía que la cola de quirquincho, más conocida como estimulante sexual 8dicen que hay que usarla recién cortada y que la están extinguiendo) era una especie de huperzia.
La nota:
Los especialistas experimentan con la planta Huperzia saururus, más conocida como cola de quirquincho, explican los investigadores en el periódico digital www.hoylauniversidad.unc.edu.ar.
Propiedades
Esa especie aunque es muy conocida por sus atributos afrodisíacos en la medicina tradicional se le reconocen propiedades estimulantes de la memoria Ese uso poco convencional nos llevó a estudiar sus componentes químicos ya que no había investigaciones que justificaran su incidencia sobre este proceso explica Mariel Agnese docente y directora del trabajo
...
Los especialistas experimentan con la planta Huperzia saururus, más conocida como cola de quirquincho, explican los investigadores en el periódico digital .
diario La Capital
Otras hierbas que estudian:
Entre las especies de la zona se detectaron que algunas tienen propiedades anticoagulantes (Flaveria bidentis), que podría servir para el desarrollo de un medicamento antitrombótico; otras antimicrobianas (Dalea elegans), útiles para combatir las cepas resistentes a los antibióticos; y también antiinflamatorias y analgésicas (Acmela decumbens), usada para calmar el dolor de muelas.
La nota:
Los especialistas experimentan con la planta Huperzia saururus, más conocida como cola de quirquincho, explican los investigadores en el periódico digital www.hoylauniversidad.unc.edu.ar.
Propiedades
Esa especie aunque es muy conocida por sus atributos afrodisíacos en la medicina tradicional se le reconocen propiedades estimulantes de la memoria Ese uso poco convencional nos llevó a estudiar sus componentes químicos ya que no había investigaciones que justificaran su incidencia sobre este proceso explica Mariel Agnese docente y directora del trabajo
...
Los especialistas experimentan con la planta Huperzia saururus, más conocida como cola de quirquincho, explican los investigadores en el periódico digital .
diario La Capital
Otras hierbas que estudian:
Entre las especies de la zona se detectaron que algunas tienen propiedades anticoagulantes (Flaveria bidentis), que podría servir para el desarrollo de un medicamento antitrombótico; otras antimicrobianas (Dalea elegans), útiles para combatir las cepas resistentes a los antibióticos; y también antiinflamatorias y analgésicas (Acmela decumbens), usada para calmar el dolor de muelas.
jueves, abril 05, 2007
Demasida memoria y neurogenesis
Why Too Much Memory May Be A Bad Thing
Science Daily — New research from Columbia University Medical Center may explain why people who are able to easily and accurately recall historical dates or long-ago events, may have a harder time with word recall or remembering the day’s current events. They may have too much memory – making it harder to filter out information and increasing the time it takes for new short-term memories to be processed and stored.
...
“In our world, we are constantly bombarded by new information so we are constantly filtering –and if we did not do this, we would be overwhelmed,” said Dr. Malleret. “Our research indicates that those with better working memory may have fewer new neurons being developed in their hippocampus, which helps them forget old and useless information sooner and enable them to take in new information faster.”
sciencedaily.com
Science Daily — New research from Columbia University Medical Center may explain why people who are able to easily and accurately recall historical dates or long-ago events, may have a harder time with word recall or remembering the day’s current events. They may have too much memory – making it harder to filter out information and increasing the time it takes for new short-term memories to be processed and stored.
...
“In our world, we are constantly bombarded by new information so we are constantly filtering –and if we did not do this, we would be overwhelmed,” said Dr. Malleret. “Our research indicates that those with better working memory may have fewer new neurons being developed in their hippocampus, which helps them forget old and useless information sooner and enable them to take in new information faster.”
sciencedaily.com
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