martes, junio 13, 2006

scyllo-inositol para el Alzheimer

In the brain of a person with Alzheimer's disease, small proteins called
amyloid â aggregate into plaques, and a protein called tau clumps into
neurofibrillary tangles
. The brain becomes inflamed and neurons atrophy and
die. It's not completely clear what kind of amyloid â peptide (monomers,
oligomeric aggregates, or fibrillar aggregates) is responsible for the
onset of disease, said St George-Hyslop of the University of Toronto.
"Because we were able to show that scyllo-inositol specifically dispersed
the high-molecular-weight oligomeric aggregates
, this study confirms that
the initiating event is the accumulation of oligomeric aggregates of
amyloid â peptide,” he said.

A Sweet Solution to Alzheimer's Disease?